Table 3.
Demographics of ICU patients treated with RRT versus without RRT
| Overall, (N = 45) | RRT(−), (N = 9) | RRT(+), (N = 36) | p value | |
|---|---|---|---|---|
| Outcome, n (%) | ||||
| Survivor | 37 (82) | 6 (67) | 31 (86) | 0.3 |
| Non-survivor | 8 (18) | 3 (33) | 5 (14) | |
| Age, years | 67 (55, 74) | 55 (32, 60) | 70 (58, 75) | 0.015 |
| Gender, n (%) | 0.7 | |||
| Female | 29 (64) | 5 (56) | 24 (67) | |
| Male | 16 (36) | 4 (44) | 12 (33) | |
| Metformin doses, mg/days | 2,550 (1,775, 3,000) | 15,000 (14,500, 15,000) | 2,550 (1,700, 3,000) | 0.037 |
| Unknown | 11 | 6 | 5 | |
| Metformin concentration, µg/mL (plasma/serum) | 60 (42, 80) | NA (NA, NA) | 60 (42, 80) | NA |
| Unknown | 32 | 9 | 23 | |
| Creatinine (median), µmol/L (plasma/serum) | 511 (246, 779) | 126 (93, 250) | 647 (371, 799) | <0.001 |
| Arterial pH | 6.90 (6.80, 7.09) | 7.25 (7.09, 7.28) | 6.88 (6.73, 7.01) | <0.001 |
| Lactate (median), mmol/L | 15 (12, 19) | 9 (6, 16) | 15 (13, 19) | 0.057 |
| Bicarbonate, mmol/L | 5.2 (2.5, 11.0) | 14.0 (11.5, 14.8) | 4.3 (2.4, 7.0) | 0.006 |
| Unknown | 13 | 3 | 10 | |
| Acute renal impairment, n (%) | ||||
| No | 10 (29) | 7 (78) | 3 (12) | <0.001 |
| Yes | 25 (71) | 2 (22) | 23 (88) | |
| Unknown | 10 | 0 | 10 | |
| Diarrhea/vomiting days before admission, n (%) | ||||
| No | 9 (41) | 0 (NA) | 9 (41) | >0.9 |
| Yes | 13 (59) | 0 (NA) | 13 (59) | |
| Unknown | 23 | 9 | 14 | |
| Chronic renal impairment, n (%) | ||||
| No | 18 (64) | 6 (100) | 12 (55) | 0.062 |
| Yes | 10 (36) | 0 (0) | 10 (45) | |
| Unknown | 17 | 3 | 14 | |
| Liver impairment/alcoholism, n (%) | ||||
| No | 14 (78) | 4 (67) | 10 (83) | 0.6 |
| Yes | 4 (22) | 2 (33) | 2 (17) | |
| Unknown | 27 | 3 | 24 | |
| Infection, n (%) | ||||
| No | 10 (59) | 2 (33) | 8 (73) | 0.2 |
| Yes | 7 (41) | 4 (67) | 3 (27) | |
| Unknown | 28 | 3 | 25 | |
| Other reasons for hypoxia, n (%) | ||||
| No | 12 (46) | 2 (33) | 10 (50) | 0.7 |
| Yes | 14 (54) | 4 (67) | 10 (50) | |
| Unknown | 19 | 3 | 16 |