Table 3. Activity of the Synthesized Compounds against Selected Mycobacterium tuberculosis Strains—MICs (μg/mL).
| compound | M. tuberculosis H37Rv | M. tuberculosis Spec. 192 (sensitive to tuberculostatics) | M. tuberculosis Spec 210 (multidrug-resistant) |
|---|---|---|---|
| 1 | 4 | 4 | 2 |
| 2 | 1 | 0.5 | ≤0.25 |
| 3 | 4 | 2 | 2 |
| 4 | 2 | 1 | 2 |
| 5 | 0.5 | 0.5 | ≤0.25 |
| 6 | 0.5 | 0.5 | ≤0.25 |
| 7 | 0.5 | 0.5 | ≤0.25 |
| 8 | 32 | 32 | 8 |
| 9 | 2 | 2 | 1 |
| 10 | 1 | 0.5 | ≤0.25 |
| 11 | 0.5 | 0.5 | ≤0.25 |
| 12 | 1 | 1 | ≤0.25 |
| 13 | 2 | 4 | 1 |
| 14 | 64 | 64 | 32 |
| 15 | 64 | 64 | 32 |
| 16 | 64 | 64 | 32 |
| 17 | 32 | 32 | 16 |
| 18 | 8 | 16 | 4 |
| 19 | 8 | 8 | 1 |
| 20 | 32 | 16 | 16 |
| 21 | 2 | 2 | 1 |
| CP | 0.5 | 0.5 | 0.25 |
| isoniazid (INH) | 0.125 | 0.125 | 16 |
| rifampicin (RMP) | 1 | 1 | 32 |
| streptomycin (SM) | 1 | 1 | 16 |
| ethambutol(EMB) | 2 | 2 | 32 |