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. 2023 May 15;8(21):18811–18822. doi: 10.1021/acsomega.3c00933

Table 2. In Vitro TS Activitya.

compounds IC50 (μM)
8 3.67 ± 0.58
9 1.01±0.41
10 1.25 ± 0.35
12 2.93 ± 0.71
15 2.57 ± 0.31
17 0.81±0.21
pemetrexed 2.81 ± 0.31
a

IC50 values are the mean ± S.D. of three separate experiments.