Table 2. Compositions and Responses According to Box–Behnken Design.
| std | run | phospholipid conc. | surfactant conc. | PS (nm) | ZP (mV) | EE% | % release |
|---|---|---|---|---|---|---|---|
| 9 | 1 | 5.5 | 1.75 | 236.5 | –21.5 | 87.9 | 73.9 |
| 3 | 2 | 1 | 3 | 348.9 | –26.9 | 71.2 | 85.9 |
| 7 | 3 | 5.5 | 1.125 | 229.8 | –23.6 | 83.9 | 69.5 |
| 1 | 4 | 1 | 0.5 | 321.5 | –34.2 | 75.5 | 76.5 |
| 10 | 5 | 5.5 | 1.75 | 237.6 | –22 | 88.1 | 74.3 |
| 8 | 6 | 5.5 | 2.375 | 284.3 | –28.6 | 84.6 | 70.9 |
| 4 | 7 | 10 | 3 | 275.9 | –27.6 | 76.3 | 65.9 |
| 6 | 8 | 7.75 | 1.75 | 259 | –26.9 | 89.6 | 72.9 |
| 2 | 9 | 10 | 0.5 | 268.3 | –30.9 | 78.9 | 58.9 |
| 5 | 10 | 3.25 | 1.75 | 254.8 | –24.6 | 83.8 | 81.6 |
| 11 | 11 | 5.5 | 1.75 | 239.8 | –20.9 | 87.6 | 74 |