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Pipeline of the fully automated segmentation and morphometric parameter estimation system. In the final segmentation image, abnormally segmented cells are indicated (abnormally small cells are marked in white, and abnormal, nonconvex cells are marked in dark gray) and excluded from the automated calculation of the morphometric parameters. IVCM, in vivo confocal microscopy; ECD, endothelial cell density; CV, coefficient of variation in cell area; HEX, percentage of hexagonal cells
