Table 1.
Baseline characteristics of 3431 MonDAFIS patients according to stroke unit level admission
| University-based comprehensive stroke centre (n = 1606) | Non univ.-based comprehensive stroke centre (n = 892) | Primary stroke centre (n = 933) | p-value | |
|---|---|---|---|---|
| Age, years (mean, SD) | 67.0 (13.1) | 66.5 (12.0) | 64.7 (13.3) | < 0.001 |
| Female sex, n (%) | 620 (38.6) | 351 (39.3) | 385 (41.3) | 0.414 |
| BMI, kg/m2 (mean (SD)) | 27.2 (5.1) | 27.7 (4.9) | 27.8 (4.9) | 0.006 |
| Index stroke | < 0.001 | |||
| Transient ischaemic attack, n (%) | 460 (28.8) | 229 (25.8) | 341 (36.6) | |
| Ischaemic stroke, n (%) | 1140 (71.3) | 659 (74.2) | 590 (63.4) | |
| NIHSS score on admission, points (median [IQR]) | 2 [1,4] | 3 [1,5] | 2 [1,4] | < 0.001 |
| Intravenous thrombolysis, n (%) | 329 (20.6) | 230 (25.9) | 186 (19.9) | 0.003 |
| Endovascular treatment, n (%) | 60 (3.8) | 36 (4.1) | 2 (0.2) | < 0.001 |
| Hemicraniectomy, n (%) | 2 (0.1) | 2 (0.2) | - | 0.287 |
| Known cardiovascular risk factors on admission | ||||
| Diabetes mellitus, n (%) | 423 (26.7) | 220 (25.0) | 239 (25.7) | 0.629 |
| Hypertension, n (%) | 1,214 (76.8) | 692 (78.5) | 703 (75.6) | 0.349 |
| Congestive heart failure, n (%) | 47 (3.0) | 20 (2.3) | 30 (3.2) | 0.443 |
| Hypercholesterolemia, n (%) | 867 (54.8) | 497 (56.5) | 434 (46.7) | < 0.001 |
| Coronary heart disease, n (%) | 205 (13.0) | 114 (12.9) | 96 (10.3) | 0.109 |
| Peripheral arterial disease, n (%) | 73 (4.6) | 36 (4.1) | 24 (2.6) | 0.032 |
| Renal impairment, n (%) | 102 (6.5) | 91 (10.3) | 69 (7.4) | 0.003 |
| Sleep apnea, n (%) | 53 (3.4) | 30 (3.4) | 13 (1.4) | 0.005 |
| Smoking/history of smoking, n (%) | 809 (50.8) | 464 (52.4) | 400 (43.2) | < 0.001 |
| Prior ischaemic stroke, n (%) | 320 (20.2) | 133 (15.1) | 129 (13.9) | < 0.001 |
| Prior TIA, n (%) | 86 (5.4) | 37 (4.2) | 27 (2.9) | 0.010 |
| Prior intracranial bleed, n (%) | 20 (1.2) | 6 (0.7) | 13 (1.4) | 0.282 |
| stroke unit beds, (median [IQR]) | 12 [12,20] | 11 [6,18] | 8 [8,10] | < 0.001 |
| In-hospital stay, days (median [IQR]) | 6 [5,9] | 7 [5,9] | 9 [7,11] | < 0.001 |
| Intervention group | 799 (49.8) | 446 (50.0) | 469 (50.3) | 0.970 |
Data are n (%), mean (SD), or median (IQR). TIA transient ischaemic attack. NIHSS National Institutes of Health Scale
P values stem from exact Fisher’s Tests, oneway ANOVA, or Kruskal–Wallis-test depending on the scaling of variables