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. 2023 Jun 1;23:246. doi: 10.1186/s12886-023-02983-5

Table 2.

Visual and ocular findings of the study subjects

Parameters Levels Groups P-value
Twins (n = 180) Non- twins (n = 182)
Monozygotic (n = 54) Dizygotic (n = 126) P-value Total
SE (D) Mean ± SD 0.976 ± 1.91 0.789 ± 1.97 0.407¥ 0.819 ± 1.963 0.49 ± 2.33 0.041¥
Median (Range) 0.94 (-3.00 to 8.37) 1.00 (-9.50 to 7.62) 0.875 (-9.5 to 8.37) 0.75 (-12.0 to 8.0)
Anisometropia (SE ≥ 1.50D) Yes 3 (5.5%) 4 (3.2%) 0.904** 7 (3.9%) 13 (7.1%) 0.25**
High Anisometropia (SE ≥ 3.00D) Yes 1 (1.8%) 2 (1.6%) 0.455* 3 (1.7%) 2 (1.1%) 0.67*
Astigmatism (%) WTR 68 (62.9%) 160 (63.5%) 0.552* 228 (63.4%) 201 (55.2%) 0.25*
ATR 4 (4.4%) 6 (2.4%) 10 (2.7%) 17 (4.7%)
Oblique 2 (1.7%) 2 (0.8%) 4 (1.1%) 4 (1.1%)
No Astigmatism 34 (31.0) 84 (33.3%) 118 (32.8%) 142 (39.0%)
Mirror Image of refractive error (%) 3 (5.6%) 2 (1.6%) 0.32* 5 (2.8%) - -
BCVA (LogMAR) Mean ± SD 0.07 ± 0.16 0.06 ± 0.14 0.557¥ 0.07 ± 0.16 0.03 ± 0.08  < 0.001¥
Median (Range) 0.0 (0.0 to 1.0) 0.0 (-0.12 to 1.0) 0 (-0.12 to 1) 0 (0 to 0.7)
Amblyopia (%) Yes 31 (57.4%) 36 (28.6%) 0.004** 67 (37.2%) 19 (10.4%) 0.005**
Strabismus (%) Orthophoria 40 (74.0%) 109 (86.5%) 0.047* 149 (82.8%) 179 (98.4%)  < 0.001*
Esotropia 5 (9.3%) 11 (8.7%) 16 (8.9%) 1 (0.5%)
Exotropia 8 (14.8%) 6 (4.8%) 14 (7.8%) 2(1.1%)
Hypertropia 0 (0.0%) 0 (0.0%) 0 (0.0%) 0 (0.0%)
DVD 1 (1.9%) 0 (0.0%) 1 (0.5%) 0 (0.0%)
Total 14 (26%) 17 (13.5%) 31 (17.2%) 3 (1.6%)
IOOA (%) Yes 6 (11.1%) 10 (7.9%) 0.67** 16 (8.9%) 29 (15.9%) 0.27**
Pattern (%) V 2 (3.7%) 5 (3.9%) 0.537* 7 (3.9%) 7 (3.8%) 0.84*
A 0 (0%) 1 (0.8%) 1 (0.5%) 2 (1.1%)
Ant. seg. anomaly Corneal abnormality 0 (0.0%) 1 (0.8%) 0.507* 1 (0.5%) 0 (0.0%)  > 0.99*
Cataract 0 (0.0%) 0 (0.0%) 0 (0.0%) 1 (0.5%)
Post. seg. anomaly Macula 4 (7.4%) 4 (3.2%) 0.35* 8 (4.4%) 4 (2.2%) 0.45*
Periphery 2 (3.7%) 4 (3.2%) 6 (3.3%) 2 (1.1%)

BCVA best corrected visual acuity, LogMAR logarithm minimum angle of resolution, SE spherical equivalent, D diopter, DVD dissociate vertical deviation, IO inferior oblique, SO superior oblique, MR medial rectus, SR superior rectus, LR lateral rectus, SR superior rectus, IR inferior rectus, WTR with- the- rule, ATR against- the- rule, standard deviation, Ant anterior, Post posterior, seg segment, P probability

*Based on Fisher Exact test

**Based on Chi-square

¥Based on independent T-test