Table 5.
Cell population content (%) found in early apoptosis, late apoptosis, necrosis, and live cells caused by PSS, PL, and cisplatin exposure 4 breast cancer cell lines
| Breast cancer cell line | Cell population (Mean (%) ± SE) | |||
|---|---|---|---|---|
| Viable cells | Early Apoptotic cells | Late Apoptotic cells | Necrotic cells | |
| MCF7 | ||||
| - Untreated | 87.74 ± 5.12 | 2.53 ± 0.81 | 22.41 ± 0.80 | 0.57 ± 0.22 |
| - PSS | 78.72 ± 7.34 | 2.55 ± 0.48 | 31.66 ± 6.74 | 0.70 ± 0.35 |
| - PL | 75.59 ± 4.70 | 6.52 ± 0.47 ** | 27.77 ± 5.05 | 0.32 ± 0.15 |
| - Cisplatin | 54.78 ± 4.65 *** | 23.76 ± 3.76 *** | 30.56 ± 11.09 | 1.41 ± 0.44 |
| T47D | ||||
| - Untreated | 96.06 ± 1.81 | 1.39 ± 0.40 | 3.24 ± 1.30 | 0.24 ± 0.09 |
| - PSS | 91.06 ± 0.62 * | 1.67 ± 0.09 | 6.56 ± 0.52 * | 0.71 ± 0.07 ** |
| - PL | 83.57 ± 1.38 *** | 4.55 ± 0.28 **** | 11.24 ± 1.24 *** | 0.65 ± 0.04 ** |
| - Cisplatin | 52.18 ± 2.88 **** | 33.26 ± 2.20 **** | 13.73 ± 0.70 **** | 0.82 ± 0.21 * |
| MDA-MB-231 | ||||
| - Untreated | 96.65 ± 1.34 | 0.93 ± 0.29 | 2.16 ± 0.99 | 0.26 ± 0.07 |
| - PSS | 87.99 ± 1.63 ** | 1.87 ± 0.13 * | 8.95 ± 1.19 ** | 1.19 ± 0.37 * |
| - PL | 89.21 ± 1.20 ** | 1.80 ± 0.05 * | 7.70 ± 0.86 ** | 1.30 ± 0.47 |
| - Cisplatin | 70.22 ± 3.49 **** | 11.87 ± 1.38 **** | 15.99 ± 2.23 *** | 1.92 ± 0.64 * |
| MDA-MB-468 | ||||
| - Untreated | 99.08 ± 0.11 | 0.56 ± 0.03 | 0.28 ± 0.07 | 0.28 ± 0.19 |
| - PSS | 88.01 ± 1.41 **** | 3.17 ± 0.54 *** | 8.33 ± 1.23 **** | 0.24 ± 0.05 |
| - PL | 90.11 ± 1.26 **** | 2.90 ± 0.32 **** | 6.80 ± 1.12 *** | 0.23 ± 0.04 |
| - Cisplatin | 43.64 ± 5.69 **** | 34.81 ± 5.04 **** | 20.40 ± 1.89 **** | 1.19 ± 0.28 |
*, **, ***, **** represented P ≤ 0.05, P ≤ 0.01, P ≤ 0.001, and P ≤ 0.0001 from statistical analysis using Unpaired t-test