Table 1.

Patient characteristics

Variable	Total population (N = 144)
Baseline
Age, years	37.7 (± 9.6)
Female (%)	89 (62%)
Ever smoker (%)	66 (65%)
EDSS at baseline	1.45 (± 1.48)
Duration from MS onset to miRNA sample, years	1.17 (± 0.65)
Untreated at miRNA sample	25 (17.4%)
T2LV at baseline (cm3, N = 121)	4.09 (± 3.06)
BPF at baseline (N = 121)	0.88 (± 0.04)
10-year follow-up
EDSS	1.88 (± 1.64)
Benign	104 (72.2%)
Not benign	40 (27.8%)
T2LV (cm3, N = 137)	5.45 (± 6.02)
BPF (N = 137)	0.84 (± 0.04)
Untreated at 10-year follow-up	3 (2%)