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. Author manuscript; available in PMC: 2023 Oct 23.
Published in final edited form as: Virology. 2022 Oct 22;577:91–98. doi: 10.1016/j.virol.2022.09.013

Table 1.

The sensitivity to skn-1 dsRNA feeding was recorded as whether the eggs laid by the treat worms can hatch.

Candidate gene Allele name Sensitivity to skn-1 dsRNA feeding Sensitivity to mCherry dsRNA feeding Temperature sensitivity Developmental defects
vrd-1 A1 - - N/A Dead eggs
vrd-2 B1 - -- N/A Egg laying defect
vrd-3 B2 - - N/A N/A
C1 - - N/A N/A
vrd-4 C2 - - N/A Slow growth
vrd-5 C3 - - N/A Egg laying defect
vrd-6 D1 - - N/A Dead eggs & slow growth
D2 - - N/A Dead eggs & slow growth
vrd-7 D4 - - N/A Egg laying defect
vrd-8 E3 - - N/A N/A
vrd-9 I3 - - N/A Slow growth
vrd-10 I4 - - N/A Egg laying defect
vrd-11 J1 - - N/A N/A
vrd-12 K1 - - N/A N/A
vrd-13 K2 - - N/A dumpy
vrd-14 K3 - - N/A N/A

-, not sensitive; + sensitive. The sensitivity to mCherry dsRNA feeding was recorded as whether the red fluorescence can be silenced in the treat worms.

The temperature sensitivity was tested as to whether the worms can breed at 25°C. egg laying defect was defined as inability to lay eggs properly, as a result, some eggs hatch in uterus.