Table 4.
Cause of Death before 1 year landmark | UCB (n=122) | MRD/MUD (n=269) | Total (n=391) | P-value |
---|---|---|---|---|
All-cause mortality | 122 (54.4%) | 269 (43.2%) | 391 (46.2%) | 0.004 |
Relapse-related mortality | 30 (24.6%) | 122 (45.4%) | 152 (38.9%) | <0.001 |
Non-relapse mortality | 92 (75.4%) | 147 (54.6%) | 239 (61.1%) | <0.001 |
Graft Rejection or Failure | 11 (9%) | 0 (0%) | 11 (2.8%) | (<0.001) |
GVHD | 6 (4.9%) | 24 (8.9%) | 30 (7.7%) | 0.24 |
Infection | 39 (32%) | 56 (20.8%) | 95 (24.3%) | 0.02 |
Organ failure | 35 (28.7%) | 56 (20.8%) | 91 (23.3%) | 0.11 |
Secondary Malignancy | 1 (0.8%) | 3 (1.1%) | 4 (1%) | >0.99 |
Unknown/cannot be determined | 0 (0%) | 8 (3%) | 8 (2%) | (0.12) |