Table 3.

Percentages of mice with seeded Aβ lesions exhibiting all three types of Aβ

	Aβ	Aβ + AβN3pE	Aβ + AβN3pE + AβpSer8	AβN3pE + AβpSer8	AβpSer8	AβN3pE
Soluble fraction	50% (n = 4)	25% (n = 2)	25% (n = 2)	0% (n = 0)	0% (n = 0)	0% (n = 0)
Dispersible fraction	20.8% (n = 5)	29.2% (n = 7)	50% (n = 12)	0% (n = 0)	0% (n = 0)	0% (n = 0)
Total fraction	62.5% (n = 5)	12.5% (n = 1)	25% (n = 2)	0% (n = 0)	0% (n = 0)	0% (n = 0)

Values with a positive percentage between 50 and 74% are highlighted in bold. The table indicates the percentages of mice with seeded Aβ lesions exhibiting all three types of Aβ (Aβ, Aβ_N3pE and Aβ_pSer8), Aβ lesions lacking Aβ_N3pE and Aβ_pSer8, and Aβ lesions showing only Aβ and Aβ_N3pE but no Aβ_pSer8. We did not observe Aβ_N3pE and Aβ_pSer8 in the absence of non-modified Aβ and Aβ_pSer8 without coexisting Aβ and Aβ_N3pE. It is interesting to note that injection of the dispersible fraction induced more frequently the induction of all types of Aβ species whereas injection of the soluble and total fraction led mainly to the induction Aβ lacking Aβ_N3pE and Aβ_pSer8.