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Caspase-8, Bax and Bcl-2 levels for compounds 5f, 5 g and staurosporine on human pancreatic cancer cell line (Panc-1).
| Compd. No. | Caspase-8 |
Bax |
Bcl-2 |
|||
|---|---|---|---|---|---|---|
| Conc (ng/ml) | Fold change | Conc (Pg/ml) | Fold change | Conc (ng/ml) | Fold reduction | |
| 5f | 2.10 | 25 | 305.50 | 37 | 0.80 | 6 |
| 5g | 1.97 | 23 | 299.40 | 36 | 0.84 | 6 |
| staurosporine | 1.75 | 21 | 276.20 | Fold reduction | 0.98 | 5 |
| Control | 0.085 | 1 | 8.25 | 1 | 5.08 | 1 |
