Table 3.

A). Names of white matter tracts that were disrupted in the largest diffusion-weighted imaging study to date of 22q11DS-psychosis+ vs. 22q11DS-psychosis- (75) B). The known anatomical region connected by each white matter tract. C). Direction of the effects in 22q11DS-psychosis+ vs. 22q11DS-psychosis- study and type of diffusivity measures altered. D). Direction of effects for largest diffusion-weighted imaging study to date of idiopathic schizophrenia vs. healthy controls and type of diffusivity measures altered (159).

A. Region	B. Anatomical brain structures known to be connected by this white matter tract	C. 22q11DS-psychosis+ vs. 22q11Ds-psychosis-	D. Idiopathic schizophrenia vs. healthy controls
Anterior limb of internal capsule	anterior and medial thalamic nuclei⇔ prefrontal cortex (160) pons⇔frontal cortex	↓ AD	↓ FA, ↓ AD, ↑ RD
Posterior limb of internal capsule	Pons/cerebellum⇔premotor and primary motor cortex Ventral thalamus⇔premotor and primary motor cortex	↓ MD	No measures statistically significant
posterior thalamic radiation	pulvinar and lateral geniculate thalamic nuclei ⇔ posterior parietal and occipital cortex (161)	↓ AD	↓ FA, ↑ MD, ↑ RD
sagittal stratum	Thalamus and brainstem ⇔ parietal, occipital, cingulate, and temporal regions of cortex (162)	↓ AD	↓ FA, ↑ MD, ↑ RD
cingulum of cingulate gyrus	Orbitofrontal cortex ⇔ cingulate gyrus ⇔ temporal lobes (163)	↓ AD	↓ FA, ↑ MD, ↑ RD
superior longitudinal fasciculus	Parietal lobes ⇔ frontal lobes (164)	↓ AD	↓ FA, ↑ MD, ↑ RD
Genu of the corpus callosum	Callosal fibers (interhemispheric)	↓ RD, ↓ MD