Fig. 6.
African origin of inversion-specific alleles. Panel A shows median allele frequencies of inversion-specific alleles from North America (FST ≥ 0.9) in inverted and standard arrangement chromosomes in population samples from Africa, Europe, and North America. Panel B shows that highly differentiated SNPs in the Zambian population (exhibiting a frequency difference ≥ 0.5 between standard and inverted chromosomes) are mostly clustered around the inversion breakpoints, with some smaller clusters (“mini-peaks”) of SNPs also visible around positions ∼19 and ∼21 Mbp. Also see supplementary figure S7, Supplementary Material online. The analyses above are based on 1,786 SNPs in total and 277 SNPs in the Zambia sample.