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. 2023 May 29;11:e15463. doi: 10.7717/peerj.15463

Table 4. Multivariate logistic regression of deference indices for hypertension.

IR surrogate index AUC (95% CI) p-value* Sensitivity (%) Specificity (%) Cut-off Youden index
To predict metabolic syndrome
BMI 0.729 [0.719−0.739] <0.001 68.86 65.05 24.76 0.339
WC 0.742 [0.732−0.751] <0.001 41.76 93.13 89.00 0.349
TyG index 0.881 [0.873−0.888] <0.001 85.38 78.14 8.88 0.635
TG/HDL 0.864 [0.856−0.872] <0.001 84.68 73.71 1.29 0.584
TyG-BMI 0.848 [0.840−0.856] <0.001 79.93 74.55 221.59 0.545
TyG-WC 0.892 [0.885−0.899] <0.001 81.29 80.72 760.77 0.620
METS-IR 0.869 [0.862−0.877] <0.001 80.75 77.32 38.45 0.581
LAP 0.887 [0.880−0.894] <0.001 82.45 79.95 34.62 0.624
VAI 0.871 [0.863−0.878] <0.001 81.50 77.87 1.78 0.594
AIP 0.864 [0.856−0.871] <0.001 84.68 73.69 0.11 0.584
To predict hypertension
BMI 0.630 [0.619−0.640] <0.001 53.68 65.76 24.80 0.194
WC 0.618 [0.607−0.629] <0.001 50.74 66.36 84.00 0.171
TyG 0.634 [0.624−0.645] <0.001 58.07 62.15 8.77 0.202
TG/HDL 0.604 [0.593−0.614] <0.001 57.14 58.63 1.16 0.158
TyG-BMI 0.659 [0.648−0.669] <0.001 65.25 58.34 211.54 0.236
TyG-WC 0.655 [0.644−0.665] <0.001 64.45 58.73 727.47 0.232
METS-IR 0.638 [0.627−0.649] <0.001 62.55 57.41 36.19 0.200
LAP 0.636 [0.626−0.647] <0.001 59.36 61.26 28.81 0.206
VAI 0.529 [0.581−0.603] <0.001 62.78 51.18 1.34 0.140
AIP 0.604 [0.593−0.614] <0.001 56.87 58.86 0.06 0.157

Note:

*

Null hypothesis, AUC = 0.5; BMI, body mass index; WC, waist circumference; TyG index, triglyceride glucose index; TG/HDL-c, triglycerides/high-density lipoprotein cholesterol ratio; TyG-BMI, TyG index with body mass index; TyG-WC, TyG index with waist circumference; METS-IR, metabolic score for insulin resistance; LAP, Lipid accumulation product; VAI, Visceral obesity index; AIP, atherogenic index of plasma.