Figure 3. Reduction of glomerular neutrophil infiltrations and neutrophil extracellular traps in Ager−/− MRL-lpr mice at 18 weeks of age.
(A) Glomerular neutrophil infiltration. The number of Ly-6G-positive cells was counted in 10 glomeruli per animal, and the mean number of positive cells per glomerulus was used for estimation (n = 8). Student’s t-test. *p < 0.05. (B) The area percentage of NETs in each glomerulus was calculated in 10 glomeruli per animal, and the mean values per glomerulus were used for estimation (n=8). Welch’s t-test. **p < 0.01. NETs, neutrophil extracellular traps, cit-Histone H3, Histone H3 (citrulline R2 + R8 + R17).