Table 4.

Multivariate analysis of factors related to portal vein tumor thrombosis

Characteristic	OR (95% CI)	P value
Ascites
Absence	1.00 (ref)	–
Presence	2.68 (1.81–3.95)	<0.001
Diameter, cm
<5	1.00 (ref)	–
≥5	2.15 (1.42–3.25)	<0.001
Albumin, g/dL
Normal range: [3.5–5.3]	1.00 (ref)	–
Low: <3.5	1.20 (0.80–1.78)	0.375
Bilirubin, mg/dL
Normal range [0.20–1.10]	1.00 (ref)	–
High: >1.10	1.26 (0.85–1.87)	0.250
INR
Normal range	1.00 (ref)	–
High: >1.0	1.17 (0.78–1.74)	0.454
Alpha-fetoprotein, ng/mL
<400	1.00 (ref)	–
≥400	3.55 (2.37–5.33)	<0.001
Tumor growth
Monofocal	1.00 (ref)	–
Multifocal	1.40 (0.96–2.04)	0.081
Infiltrative	11.75 (6.01–22.95)	<0.001
Massive	3.38 (1.34–8.50)	0.010
Gastropathy
Absent/mild	1.00 (ref)	–
Moderate/severe	1.15 (0.77–1.71)	0.505

P values in bold are significant.

CI, confidence interval; INR, International Normalized Ratio; OR, odds ratio.