Table 1.
Classification of diabetes neuropathy [adapted from Pop-Busui et al. (2)].
| I. DIFFUSE NEUROPATHY | ||
|---|---|---|
| A. Distal symmetrical polyneuropathy (DSPN) | ||
| i) Primary large fibre involvement | ||
| ii) Primarily small fibre involvement | ||
| iii) Mixed large and small fibre involvement (commonest) | ||
| B. Autonomic neuropathy | ||
|
i) Cardiovascular
Resting tachycardia Orthostatic hypotension Reduced heart-rate variability Malignant arrhythmias |
||
|
ii) Gastrointestinal
Diabetes gastropathy Diabetes enteropathy Colonic dysmotility |
||
|
iii) Urogenital
Erectile dysfunction Neurogenic bladder Female sexual dysfunction |
||
|
iv) Sudomotor dysfunction
Gustatory sweating Distal hypohydrosis |
||
| v) Hypoglycaemic unawareness | ||
| vi) Pupillary abnormalities | ||
| II. Mononeuropathy (mononeuritis multiplex) | ||
| A. Isolated cranial nerve (III/VI) palsy | ||
| B. Peripheral nerve palsies (ulnar, median, femoral, peroneal) | ||
| C. Mononeuritis multiplex | ||
| III. Radiculopathy or polyradiculopathy | ||
| A. Radiculoplexus neuropathy (lumbosacral radiculopathy, diabetes amyotrophy) | ||
| B. Thoracic radiculopathy | ||