Table 1.
Patient Demographics
| Patient Metric | Parameter | Control Subjects (n = 40) | Patients with Ichthyosis n = 54) | P-value, Control Subjects Verus Patients with Ichthyosis | Patients with NS (n = 7) | Patients with LI (n = 16) | Patients with CIE (n = 18) | Patients with EI (n = 13) | P-value, Subtypes |
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| Age (y) | Mean ± SD (range) | 25.6 ± 17 (1.3–65) |
25.4 ± 18 (1–70.8) |
0.954 | 23.5 ± 14 (6.3–43.2) |
30.5 ± 16 (9.2–56.9) |
19.8 ± 16 (1–48.7) | 27.4 ± 22 (1.1–70.8) |
0.355 |
| Sex | F/M | 21/19 | 30/24 | 0.836 | 5/2 | 11/5 | 7/11 | 7/6 | 0.273 |
| Racial identity | AP/As/B/W/other | 0/1/3/33/2 | 1/3/5/39/5 | 0.893 | 0/0/1/5/1 | 0/0/1/13/2 | 1/2/2/11/2 | 0/1/1/10/0 | 0.869 |
| IASI score | Mean ± SD | NA | 24.9 ± 9 (2.4–43.2) |
NA | 26.3 ± 9 (16.2–37.2) |
26.1 ± 7 (12–40.2) |
24.7 ± 10 (10.8–41.4) | 23.1 ± 11 (2.4–43.2) |
0.827 |
Abbreviations: AP, American Indian/Pacific Islander; As, Asian; B, Black; CIE, congenital ichthyosiform erythroderma; EI, epidermolytic ichthyosis; F, female; IASI, Ichthyosis Area Severity Index; LI, lamellar ichthyosis; M, male; NA, not applicable; NS, Netherton syndrome; W, White.
Other denotes other racial identities unknown.