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. 2023 Mar 27;37(6):4193–4223. doi: 10.1007/s00464-023-09981-0

Table 3.

Robotic surgical systems for visualization in natural orifice procedures, by year

Name Visualization type DOF Manipulation type Actuation method Control type & level of automation Control interface Development stage Year Clinical application
Camera Total
Flex system (Medrobotics Corp., USA) [29, 68, 69]

3D HD

Dual 1920 × 1080 pixel

80° field of view

180° articulation, horizontal, vertical, rotation, zoom Cable-driven

Teleoperated

Master–slave

Open console

Single-port control joystick

Commercial 2015 (FDA)

Surgery—minimally invasive

Transoral surgery (oropharyngeal, hypopharyngeal, laryngeal procedures)

Obstetric/gynecologic applications

MONARCH platform (Auris Health, Inc., USA)a [14, 7073] 660p x central airways & periphery vision 10

Insertion, retraction, articulation

180° in all direction

Cable-driven

Teleoperated

Master–slave

Hand-held controller (joysticks & buttons) Commercial 2018 (FDA)

Investigational procedure

Robotic bronchoscopy for peripheral pulmonary lesion biopsy

Surgery—minimally invasive

Urology—percutaneous nephrolithotomy

STRAS (ICubeb) [13, 16] 2 10 Rotation, deflection, translation Motor (tendon-driven)

Teleoperated

Master–slave

Handle shaft on L-shaped bracket, two small four-way finger joysticks to operate endoscope Research prototype (animal studies) 2018

Surgery—minimally invasive

Treatment of tumor in rectum and sigmoid colon

Gastrointestinal tract surgery

Endoscopic submucosal dissection (ESD) in animal model

i2Snake (Hamlyn Centre, UK) [74]

3 mm

640 × 480 pixels

7 Tendon driven actuated by EC motors

Teleoperated

Master–slave

Hand-held gripper

Foot pedal for switching modes

Research prototype (lab studies) 2018

Surgery—minimally invasive

Transoral surgery

Tumor resection, sleep-apnea surgery

Ion endoluminal system (Intuitive Surgical Inc., USA) [7577]

Removable vision probe

90° field of view

0° direction of view

180° in all direction

(pitch & yaw)

Electromechanically (servo/stepper motors & software)

Teleoperated

Master–slave

Hand control (trackball & scroll wheel) Commercial 2019 (FDA)

Investigational procedure

Minimally invasive peripheral lung biopsy (bronchoscopy)

Endoscopic Therapeutic Robot System (ETRS) (Kyushu Institute of Technology, Japan)c [78] 120° field of view 4 Up/down & left/right angulation, insertion/retraction, rotation Motor

Teleoperated

Master–slave

Hand controls (Geomagic Touch) Research prototype (animal studies) 2019

Surgery—minimally invasive

Endoscopic submucosal dissection (ESD) in porcine model

K-FLEX (EasyEndo Surgical, Korea) [79] High definition 4 14 Deflection, translation, rotation Wire cable & motor

Teleoperated

Master–slave

Hand interface switched by foot clutch Research prototype (ex vivo porcine study) 2020

Surgery—minimally invasive

Possible application for gastrointestinal tract, ENT surgeries

Three-Limb Robotic System (Nanyang Technological University, Singapore)d [16, 80, 81]

120° field of view

0° forward viewing

4 13 Up/down, left/right, in/out, rotation Tendon-sheath mechanism & motors

Teleoperated

Master–slave

Open master console

Two hand interfaces

One foot interface to control endoscope

Research prototype (ex vivo porcine study) 2021

Surgery—minimally invasive

Transoral robotic surgery

Gastrointestinal tract surgery

Endoscopic resection

Endoluminal Surgical System (EndoQuest Robotics, USA)e [82, 83] 3.7 mm HD robotic camera 7 Advanced flexibility & dexterity

Teleoperated

Master–slave

Open surgeon console—hand controllers & foot pedal (clutch) Research prototype (clinical trial) 2021

Surgery—minimally invasive

Transanal endoluminal procedures; colorectal endoscopic submucosal dissection (ESD)

aAuris Health previously acquired Hansen Medical, manufacturer of Magellan & Sensei robotic systems. Auris Health was later acquired by Johnson & Johnson, which plans to build Ottava.

bSTRAS is a robotic version of Anubiscope (IRCAD & KARL STORZ Endoskope)

cThe endoscope is controlled by endoscopic operation robot (EOR)

dNanyang Technological University has also produced the robotic system EndoMaster (EndoMaster Pte Ltd., Singapore). However, it requires manual operation of the endoscope

eEndoluminal Surgical System was previously known as ColubrisMX ELS System