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. 2023 Jun 1;13:8899. doi: 10.1038/s41598-023-35092-w

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The landscape of somatic genetic alterations in HRR-related genes across cancer types. (A) Mutation landscape of HRR-related genes across different cancer types. Oncoprint plot on the left illustrates the overall frequency of mutations in HRR-related genes (rows, with gene names listed to the left) across 9140 samples. The color key at the bottom indicates the type of cancer. (B) Histogram showing the mutation frequency of HRR-related genes in different cancer types. (C) A heatmap illustrating the variable frequency of CNV deletion in different cancer types. Cancer types (columns) and genes associated with the HRR (rows).