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. 2023 Apr 22;54(2):619–627. doi: 10.1007/s42770-023-00961-z

Table 3.

Base mutation sites and amino acid replacement for GCN4 in Candida albicans strains

No. of strains ITR sensitivity Base mutation sites Amino acid replacement
17 R A106Ta/T513C/C732T T36S/No/No
54 R A147C/C732T No/No
58 R G624A No
67 R A106Ta/C732T T36S/No
96 R T513C/C732T No/No
105 R T513C/C732T No/No
115 R A106Ta/T513C/C732T T36S/No/No
188 R A106Ta/C426T/T576A/G624A T36S/No/No/No
73 S C732T No
80 S T513C/C732T No/No
94 S G624A No
117 S T513C/C732T No/No

R, only resistant to ITR; S, susceptible to all ITR, FCA, VRC; aMissense mutation sites; T, threonine; S, serine