Table 1.

Physicochemical properties of PHI-Der.

Name	Numerical value
Molecular weight	330.34 g/mol
Heavy atoms	24
Aromatic heavy atoms	12
Fraction Csp3	0.33
Rotatable bonds	2
H-bond acceptors	6
H-bond donors	4
Ring count	4
Aromatic ring count	2
Molar refractivity	83.91 m3/mol
Topological polar surface area (TPSA)	99.38 Å2
Lipid-water partition coefficient (log)	2.58 log(mol/mol)
Acid dissociation constant (pKa)	8.32 log(mol/mol)
Water solubility (log)	−3.75 log(mol/L)