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. 2023 May 19;10:1127261. doi: 10.3389/fcvm.2023.1127261

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© 2023 Pohl, Göz, Gärtner, Brodehl, Cimen, Saguner, Schulze-Bahr, Walhorn, Anselmetti and Milting.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic overview of the DSC2 constructs used for transient transfection of (A) HT-1080 cells and hIPSC-derived cardiomyocytes for confocal microscopy and (B) HEK293 c18 cells for the secretion assay. SP, signal peptide; PD, prodomain; eYFP, enhanced yellow fluorescence protein; DSC2/ECD, extracellular cadherin domain of desmocollin-2.