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. 2023 May 19;14:1173069. doi: 10.3389/fimmu.2023.1173069

Figure 2.

Figure 2

IL-33-ST2 signaling is dispensable for OVA-challenged food allergic responses after epicutaneous treatment with OVA and δ-toxin on the non-tape-stripped skin. (A, D) Frequency of diarrhea in OVA-administered mice after epicutaneous treatment with OVA ± δ-toxin on the non-tape-stripped skin of (A) WT and KitW-sh/W-sh mice and (D) WT and ST2 knockout (KO) mice. (B, E) Serum levels of OVA-specific IgE in (B) WT and KitW-sh/W-sh mice and (E) WT and ST2 KO mice after the final administration of OVA. (C, F) The numbers of jejunum mast cells in (C) WT and KitW-sh/W-sh mice and (F) WT and ST2 KO mice after the final administration of OVA. (A–F) Data are representative of two independent experiments. (B, C, E, F) Means ± SD have been plotted. **, P < 0.01.