Figure 4.

Elucidative Design. After 24 hours of infection with Streptococcus pneumoniae, an increase in the migration of macrophages and neutrophils into the alveolus is observed. However, this migration is reduced in alcohol-fed mice, although this group also shows an increase in CXCL1 in plasma and BALF. In contrast to water-fed mice, which have low levels of nitric oxide at baseline, alcohol-fed mice have a higher bacterial load and higher alveolar nitric oxide production compared to untreated mice.