Table 1.

Single predictor regression analyses for all putative psychosocial predictors in the antidepressant discontinuation group

Predictor	DSS success			DSS positive effects			DSS negative effects			Objective discontinuation
	b	t	R2	b	t	R2	b	t	R2	OR	z
Sociodemographic data
Age	0.00	0.13	<0.001	0.03	0.59	0.001	−0.07	−1.52	0.008	0.99	−0.83
Gender (female v. male)	−0.46	−0.63	0.002	−0.74	−0.51	0.001	−0.42	−0.32	<0.001	0.43**	−2.84
Education (high v. low)	−0.36	−0.52	0.001	0.93	0.68	0.002	−2.16+	−1.72	0.011	1.19	0.66
Clinical and medication history
Duration of disorder	−0.01	−0.41	0.001	−0.02	−0.36	0.001	0.00	0.08	<0.001	1.02	−0.90
Discontinuation of SSRI	0.42	0.67	0.002	−0.92	−0.73	0.002	−0.10	−0.08	<0.001	1.18	0.07
Discontinuation of SNRI	−1.14+	−1.80	0.012	−1.01	−0.78	0.002	0.33	0.28	<0.001	0.79	−0.92
Discontinuation of tri/tetracyclic AD	2.11*	2.59	0.026	2.55	1.54	0.009	1.39	0.90	0.003	3.08**	3.10
Duration of medication intake	0.03	0.65	0.002	0.07	0.86	0.003	−0.01	−0.12	<0.001	0.98	−1.17
Multiple discontinued drugs (v. one)	2.37***	3.38	0.042	3.88**	2.71	0.028	−0.79	−0.59	0.001	1.37	1.11
Concomitant medication	−0.36	−0.42	0.001	−4.01*	2.36	0.022	1.44	0.91	0.003	0.61	−1.44
Professional support
Shared decision-making	0.11***	3.74	0.051	0.03	0.59	0.001	−0.12*	−2.24	0.019	0.99	−0.60
Therapeutic alliance	0.75***	4.20	0.065	0.17	0.45	0.001	−0.99**	−2.95	0.033	0.91	−1.35
Psychotherapy during attempt	0.22	0.35	<0.001	−0.70	−0.55	0.001	−0.67	−0.58	0.001	0.97	−0.14
Circumstances
Unstable situation	0.02	0.53	0.001	0.014	0.66	0.002	0.04	0.66	0.002	1.03*	2.15
Discontinuation strategy
Preparation	0.02	0.05	<0.001	0.45	0.64	0.002	−1.15+	−1.79	0.012	0.77+	−1.89
Followed a tapering plan	−0.06	−0.21	<0.001	−0.31	−0.55	0.001	−0.27	−0.52	0.001	0.67***	−3.38
Adjustment phasesa	0.48+	1.71	0.014	0.72	1.24	0.008	−1.27**	−2.39	0.028	0.71**	−2.99
Flexible reductiona	−0.47	−1.49	0.011	0.09	0.13	<0.001	0.56	0.92	0.004	1.20	1.44
Accelerated pacing (v. slow)a	2.61**	2.80	0.049	−1.05+	−0.55	0.002	−0.37	−0.24	0.051	2.40*	2.17
Coping strategies
Physical care	−0.49	−1.33	0.007	1.37+	1.86	0.013	−0.45	−0.66	0.002	0.96	−0.27
Relaxation	−0.08	0.17	<0.001	3.08***	3.67	0.051	−0.07	−0.09	<0.001	0.95	−0.27
Mindful awareness	1.50***	4.72	0.080	3.44***	5.41	0.102	−3.76***	−6.54	0.145	0.98	−0.14
Self-compassion	0.84*	2.52	0.024	3.40***	5.32	0.102	−2.62***	−4.33	0.069	1.12	0.85
Supportive relationships	0.94**	2.79	0.030	2.73***	4.14	0.064	−2.98***	−4.92	0.087	0.78+	−1.82
Supportive structures	0.53	1.62	0.010	3.25***	4.78	0.084	−2.79***	−4.39	0.071	0.71*	−2.40
Drug consumption	0.53	1.51	0.009	0.62	0.86	0.003	0.09	0.14	<0.001	1.26	1.62

Note: Regression analyses with one predictor and one dependent variable.

^aOnly participants who indicated to have followed a tapering plan responded to the questions on the details of the tapering plan (n = 200).

Significance levels: +p < 0.1, *p < 0.05, **p < 0.01, ***p < 0.001. Significant effects are printed in bold.