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. 2021 Dec 23;53(7):3085–3095. doi: 10.1017/S0033291721005146

Table 2.

Single predictor regression analyses for all putative psychosocial predictors in the antipsychotic discontinuation group

Predictor DSS success DSS positive effects DSS negative effects Objective discontinuation
b t R2 b t R2 b t R2 OR z
Sociodemographic data
Age 0.01 0.13 <0.001 0.02 0.24 0.001 −0.09 −1.08 0.012 0.99 −0.69
Gender (female v. male) −0.16 −0.14 <0.001 −3.46 −1.59 0.027 0.07 0.03 <0.001 0.31* −2.33
Education (high v. low) 0.02 0.02 <0.001 −0.65 −0.30 0.001 −2.45 −1.25 0.017 0.76 0.62
Clinical and medication history
Duration of disorder −0.01 −0.17 <0.001 0.12 0.90 0.008 −0.02 −0.13 <0.001 1.00 0.14
Discontinuation of 1st gen AP −1.03 −0.93 0.009 −2.38 −1.06 0.012 4.05* 2.01 0.042 0.74 −0.64
Discontinuation of 2nd gen AP 1.14 0.74 0.006 6.74* 2.19 0.049 −6.95* −2.51 0.064 2.40 1.32
Duration of medication intake 0.06 0.85 0.008 0.16 1.15 0.014 −0.05 −0.44 0.002 0.99 −0.26
Multiple discontinued drugs (v. one) −0.32 −0.32 0.001 −1.05 −0.51 0.003 4.33* 2.41 0.060 0.57 −1.33
Concomitant medication 0.98 0.81 0.007 −0.92 −0.37 0.001 0.93 0.42 0.002 0.76 0.54
Professional support
Shared decision-making 0.06 1.43 0.022 −0.43 −0.75 0.006 −0.06 −0.75 0.006 0.98 −1.39
Therapeutic alliance 0.18 0.64 0.004 −0.42 −0.75 0.006 −0.06 0.13 <0.001 0.69** −0.37
Psychotherapy during attempt −0.30 −0.30 0.001 −4.15* −2.07 0.045 3.31+ 1.81 0.034 0.79 −0.55
Circumstances
Unstable situation −0.01 −0.28 0.001 −0.16 −1.53 0.024 0.27** 2.92 0.085 1.05* 1.97
Discontinuation strategy
Preparation 1.12* 2.17 0.049 1.32 1.23 0.016 −2.14* 2.25 0.052 0.71 −1.49
Followed a tapering plan 0.48 1.07 0.012 −0.58 −0.63 0.004 −0.50 −0.59 0.004 0.74 −1.50
 Adjustment phasesa 1.20** 2.84 0.098 2.44** 2.79 0.094 −3.02*** 3.98 0.174 1.02 0.10
 Flexible reductiona −0.82+ −1.80 0.042 1.59+ 1.69 0.037 0.85 0.99 0.013 1.54* 2.03
 Accelerated pacing (v. slow)a −1.20 −0.89 0.013 −4.56 −1.56 0.039 1.47 0.57 0.005 0.51 −1.07
Coping strategies
Physical care −1.30* −2.43 0.061 1.18 1.04 0.012 0.98 0.95 0.010 0.81 −0.91
Relaxation 0.40 0.61 0.004 4.99*** 3.91 0.145 2.17+ −1.75 0.033 1.10 0.33
Mindful awareness 1.73*** 3.96 0.150 3.88*** 4.27 0.168 −3.25*** −3.85 0.141 0.89 −0.59
Self-compassion 0.23 0.44 0.002 3.45** 3.36 0.112 −1.91+ −1.96 0.041 0.98 −0.07
Supportive relationships 1.38* 2.60 0.071 3.74*** 3.55 0.123 −4.22*** −4.57 0.188 0.77 −1.13
Supportive structures 0.88 1.61 0.028 4.41*** 4.15 0.161 −3.58*** 3.62 0.127 0.84 −0.71
Drug consumption −0.50 1.16 0.015 0.58 0.64 0.005 0.98 1.19 0.016 1.52+ 1.90

Note: Regression analyses with one predictor and one dependent variable.

a

Only participants who indicated to have followed a tapering plan responded to the questions on the details of the tapering plan (n = 76).

+p < 0.1, *p < 0.05, **p < 0.01, ***p < 0.001. Significant effects are printed in bold.