Table 3.
Associations between neuropeptides with psychotic symptoms in FES and BD groups.
Unstandardized coefficients | Standardized coefficients | t | p | R 2 | Adjusted R2 | F | ||
---|---|---|---|---|---|---|---|---|
B | SE | Beta | ||||||
P2 | ||||||||
Constant | 7.19 | 2.06 | – | 3.49 | <0.01 | 0.062 | 0.050 | F(1, 78) = 5.14, p < 0.05 |
Log10 oxytocin | −1.99 | 0.88 | −0.25 | −2.27 | <0.05 | |||
N2 | ||||||||
Constant | 7.12 | 2.10 | – | 3.39 | <0.01 | 0.054 | 0.042 | F(1, 78) = 4.45, p < 0.05 |
Log10 oxytocin | −1.89 | 0.90 | −0.23 | −2.11 | <0.05 | |||
N3 | ||||||||
Constant | 7.54 | 2.08 | 3.62 | <0.01 | 0.061 | 0.049 | F(1, 78) = 5.03, p < 0.05 | |
Log10 oxytocin | −1.99 | 0.89 | −0.25 | −2.24 | <0.05 | |||
G9 | ||||||||
Constant | 7.63 | 2.43 | – | 3.15 | <0.01 | 0.049 | 0.037 | F(1, 78) = 4.03, p < 0.05 |
Log10 oxytocin | −2.08 | 1.04 | −0.22 | −2.01 | <0.05 | |||
BPRS deficiency energy factor score | ||||||||
Constant | 24.47 | 5.90 | 4.15 | <0.001 | ||||
Log10 oxytocin | −6.36 | 2.52 | −0.28 | −2.53 | <0.05 | 0.076 | 0.064 | F(1, 78) = 6.40, p < 0.05 |
Constant | 32.01 | 6.89 | – | 4.65 | <0.001 | 0.122 | 0.099 | F(2, 77) = 5.36, p < 0.01 |
Log10 oxytocin | −15.03 | 5.00 | −0.65 | −3.04 | < 0.01 | |||
Log10 substance P | 8.15 | 4.04 | 4.33 | 2.02 | < 0.05 |
Independent variables: age, gender, education years, BMI, log10 α-MSH, log10 β-endorphins, log10 neurotensin, log10 orexin A, log10 oxytocin and log10 substance P. P2, PANSS positive symptom scale item 2; N2, PANSS negative symptom scale item 2; N3, PANSS negative symptom scale item 3; G9, PANSS general pathology symptom scale item 9; PANSS, The Positive and Negative Syndrome Scale; BPRS, The Brief Psychiatric Rating scale.