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. 2023 May 19;14:1180720. doi: 10.3389/fpsyt.2023.1180720

Table 3.

Associations between neuropeptides with psychotic symptoms in FES and BD groups.

Unstandardized coefficients Standardized coefficients t p R 2 Adjusted R2 F
B SE Beta
P2
Constant 7.19 2.06 3.49 <0.01 0.062 0.050 F(1, 78) = 5.14, p < 0.05
Log10 oxytocin −1.99 0.88 −0.25 −2.27 <0.05
N2
Constant 7.12 2.10 3.39 <0.01 0.054 0.042 F(1, 78) = 4.45, p < 0.05
Log10 oxytocin −1.89 0.90 −0.23 −2.11 <0.05
N3
Constant 7.54 2.08 3.62 <0.01 0.061 0.049 F(1, 78) = 5.03, p < 0.05
Log10 oxytocin −1.99 0.89 −0.25 −2.24 <0.05
G9
Constant 7.63 2.43 3.15 <0.01 0.049 0.037 F(1, 78) = 4.03, p < 0.05
Log10 oxytocin −2.08 1.04 −0.22 −2.01 <0.05
BPRS deficiency energy factor score
Constant 24.47 5.90 4.15 <0.001
Log10 oxytocin −6.36 2.52 −0.28 −2.53 <0.05 0.076 0.064 F(1, 78) = 6.40, p < 0.05
Constant 32.01 6.89 4.65 <0.001 0.122 0.099 F(2, 77) = 5.36, p < 0.01
Log10 oxytocin −15.03 5.00 −0.65 −3.04 < 0.01
Log10 substance P 8.15 4.04 4.33 2.02 < 0.05

Independent variables: age, gender, education years, BMI, log10 α-MSH, log10 β-endorphins, log10 neurotensin, log10 orexin A, log10 oxytocin and log10 substance P. P2, PANSS positive symptom scale item 2; N2, PANSS negative symptom scale item 2; N3, PANSS negative symptom scale item 3; G9, PANSS general pathology symptom scale item 9; PANSS, The Positive and Negative Syndrome Scale; BPRS, The Brief Psychiatric Rating scale.