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. 2023 May 19;14:1180720. doi: 10.3389/fpsyt.2023.1180720

Table 4.

Associations between neuropeptides and HAMD scores item 6 in the three patient groups.

Unstandardized coefficients Standardized coefficients t p R 2 Adjusted R2 F
B SE Beta
Constant 0.38 0.077 4.92 <0.001 0.30 0.30 F(1, 96) = 41.88, p < 0.001
MDD group 0.95 0.15 0.55 6.47 <0.001
Constant 2.91 0.81 3.57 <0.01 0.37 0.36 F(2, 95) = 27.69, p < 0.001
MDD group 0.97 0.14 0.56 6.90 <0.001
Log10 endorphin −0.96 0.31 −0.25 −3.12 <0.01

Independent variables: age, gender, education, BMI, group status, log10 α-MSH, log10 β-endorphins, log10 neurotensin, log10 orexin A, log10 oxytocin and log10 substance P, HAMD: 17 item Hamilton depression rating scale. MDD, major depressive disorders.