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. 2023 May 19;10:1156474. doi: 10.3389/fcvm.2023.1156474

Table 7 .

Adapted from the Heart Rhythm Society expert consensus statement, recommendations for ICD implantation in cardiac sarcoidosis patients (40).

Class Recommendation
I ICD implantation is recommended in patients meeting at least one of the following criteria:
  • 1) 

    Sustained ventricular tachycardia, including prior cardiac arrest.

  • 2) 

    LV EF ≤35% despite optimal medical therapy and immunosuppression (in the presence of active inflammation)

IIa ICD implantation can be useful in patients, regardless of their LV function, meeting at least one of the following criteria:
  • 1) 

    Indication for permanent pacemaker implantation

  • 2) 

    Status after syncope or pre-syncope likely to be of arrhythmogenic etiology

  • 3) 

    Inducible sustained ventricular tachycardia (whether monomorphic or polymorphic) or clinically relevant ventricular fibrillation

IIb ICD implantation may be considered in patients with LVEF in the range of 36%–49% and/or an RV ejection fraction <40%, despite optimal medical therapy for heart failure and a period of immunosuppression (if there is active inflammation).
III ICD implantation is not recommended in patients without a history of syncope, with normal LV and right ventricular EF, absence of LGE on CMR, with negative electrophysiology study, and no indication for permanent pacing. Nonetheless, these patients should be closely monitored for their LV and right ventricular function ICD implantation is not recommended in patients meeting at least one of the following criteria:
  • 1) 

    Incessant ventricular tachycardias

  • 2) 

    Severe NYHA class IV heart failure

CMR, cardiac magnetic resonance; EF, ejection fraction; ICD, implantable cardioverter/defibrillator; LGE, late gadolinium enhancement; LV, left ventricular; NYHA, New York Heart Association.