(A) Body weight of miR-33bfl/fl KI mice and Ayu1-Cre/miR-33bfl/fl KI mice at 8 wk of age. n = 5 mice per group. (B) Relative expression levels of miR-33b in the livers, epididymal white adipose tissues, hearts, and gastrocnemius muscles of miR-33bfl/fl KI mice and Ayu1-Cre/miR-33bfl/fl KI mice. n = 4 mice per group; **P < 0.01, unpaired t test. (C) Relative expression levels of miR-33a in the livers, epididymal white adipose tissues, hearts, and gastrocnemius muscles of miR-33bfl/fl KI mice and Ayu1-Cre/miR-33bfl/fl KI mice. n = 4 mice per group. (D) Relative expression levels of Srebf1, Srebf2, Abca1, Cpt1a, and Crot in the livers of miR-33bfl/fl KI mice and Ayu1-Cre/miR-33bfl/fl KI mice. n = 4 mice per group; *P < 0.05, unpaired t test.