Table 2.
Serum data of miR-33fl/fl KI and Alb-Cre/miR-33bfl/fl KI mice fed a 45% HFD.
| miR-33bfl/fl KI | Alb-Cre/miR-33bfl/fl KI | ||
|---|---|---|---|
| TP (g/dl) | 4.33 ± 0.20 | 4.43 ± 0.08 | |
| ALB (g/dl) | 2.73 ± 0.08 | 2.77 ± 0.04 | |
| AST (IU/l) | 105.8 ± 27.4 | 45.7 ± 2.6 | * |
| ALT (IU/l) | 63.3 ± 16.2 | 26.7 ± 4.9 | * |
| ALP (IU/l) | 237.5 ± 51.3 | 213.1 ± 14.5 | |
| LDH (IU/l) | 663.5 ± 100.1 | 420.4 ± 55.6 | * |
| T-BIL (mg/dl) | 0.241 ± 0.103 | 0.075 ± 0.007 | |
| TBA (μmol/l) | 29.8 ± 20.0 | 1.43 ± 0.20 | |
| T-Cho (mg/dl) | 71.8 ± 12.8 | 139.1 ± 9.2 | ** |
| LDL-C (mg/dl) | 5.5 ± 0.7 | 3.2 ± 1.3 | * |
| HDL-C (mg/dl) | 38.8 ± 7.9 | 64.6 ± 8.0 | ** |
| TG (mg/dl) | 25.1 ± 4.0 | 23.9 ± 4.2 | |
| NEFA (μEq/l) | 428.0 ± 41.2 | 433.6 ± 30.8 |
Male mice were fed a 45% HFD from the age of 8 wk for 12 wk. Values are the mean ± S.E.M., n = 6, 7 each; *P < 0.05 and **P < 0.01, unpaired t test.