Table 1.
Demographic, anthropometric and clinical characteristics, comorbidities and patient-reported outcomes according to four frailty-resilience phenotypes.
| Fit & resilient N = 95 (41%) | Fit & non resilient N = 65 (28.0%) | Frail & resilient N = 23 (9.9%) | Frail & non resilient N = 49 (21.1%) | Total 232 (100%) | P | |
|---|---|---|---|---|---|---|
| Demographic, anthropometric and clinical characteristics at MPC visit | ||||||
| Age, years, median (Q1-Q3) [N0] | 60.0 (51.0–66.5) [95] | 58.0 (49.0–66.0) [65] | 54.0 (51.5–67.0) [23] | 58.0 (53.0–68.0) [49] | 58.0 (50.0–67.0) [232] | 0.8 |
| Male sex, N (%) | 66 (69.5%) | 39 (60.0%) | 11 (47.8%) | 25 (51.0%) | 141 (60.8%) | 0.09 |
| Body mass index, kg/m2, median (IQR) [N0] | 29.1 (25.9–32.0) [79] | 28.0 (25.8–31.0) [59] | 30.43 (27.1–34.6) [23] | 30.7 (25.5–33.9) [43] | 29.3 (25.8–32.4) [204] | 0.14 |
| ASCVD risk score, median (Q1-Q3) [N0] | 10.4 (5.3–20.4) [56] | 7.7 (4.0–17.5) [39] | 5.7 (4.3–10.9) [13] | 8.4 (2.5–11.6) [28] | 9.1 (4.4–17.6) [136] | 0.41 |
| Physical activity, N (%) | < 0.001 | |||||
| Low physical activity | 52 (54.7%) | 37 (56.9%) | 21 (91.3%) | 46 (93.9%) | 156 (67.2%) | |
| Moderate physical activity | 39 (41.1%) | 26 (40.0%) | 2 (8.7%) | 3 (6.1%) | 70 (30.2%) | |
| Intense physical activity | 4 (4.2%) | 2 (3.1%) | 0 (0.0%) | 0 (0.0%) | 6 (2.6%) | |
| Metabolic syndrome, N (%) | 11 (11.6%) | 13 (20.0%) | 6 (26.1%) | 10 (20.4%) | 40 (17.2%) | 0.43 |
| Diabetes, N (%) | 10 (10.5%) | 7 (10.8%) | 4 (17.4%) | 5 (10.2%) | 26 (11.2%) | 0.89 |
| Obesity, N (%) | 29 (30.3%) | 19 (29.2%) | 12 (52.2%) | 24 (49.0%) | 84 (36.2%) | 0.06 |
| PACS clusters | ||||||
| Respiratory cluster, N (%) | 36 (37.9%) | 35 (53.9%) | 18 (78.3%) | 39 (79.6%) | 128 (55.2%) | < 0.001 |
| Neurocognitive cluster, N (%) | 19 (20.0%) | 24 (36.9%) | 12 (52.2%) | 27 (55.1%) | 82 (35.3%) | < 0.001 |
| Musculoskeletal cluster, N (%) | 18 (19.0%) | 14 (21.5%) | 12 (52.2%) | 23 (46.9%) | 67 (28.9%) | < 0.001 |
| Psychological cluster, N (%) | 22 (23.2%) | 19 (29.2%) | 11 (47.8%) | 27 (55.1%) | 79 (34.1%) | < 0.001 |
| Sensory cluster, N (%) | 14 (14.7%) | 15 (23.1%) | 6 (26.1%) | 14 (28.6%) | 49 (21.1%) | 0.22 |
| Dermatologic cluster, N (%) | 10 (10.5%) | 13 (20.0%) | 6 (26.1%) | 13 (26.5%) | 42 (18.1%) | 0.07 |
| NAFLD cluster, N (%) | 31 (32.6%) | 29 (44.6%) | 12 (52.2%) | 21 (42.9%) | 93 (40.1%) | 0.42 |
| PACS syndrome, N (%) | 59 (62.1%) | 48 (73.9%) | 22 (95.7%) | 44 (89.8%) | 173 (74.6%) | < 0.001 |
| Geriatric syndromes | ||||||
| Falls in the last year, N (%) | 11 (11.6%) | 3 (4.6%) | 8 (34.8%) | 13 (26.5%) | 35 (15.1%) | < 0.001 |
| Polypharmacy, N (%) | 12 (12.6%) | 16 (24.6%) | 12 (52.2%) | 17 (34.7%) | 57 (24.6%) | < 0.001 |
| Walked less in the last year, N (%) | 36 (37.9%) | 27 (41.5%) | 18 (78.3%) | 35 (71.4%) | 116 (50.0%) | < 0.001 |
| Loneliness, N (%) | 9 (9.5%) | 10 (15.4%) | 5 (21.7%) | 20 (40.8%) | 44 (19.0%) | < 0.001 |