Skip to main content
. 2023 Jun 2;13:8960. doi: 10.1038/s41598-023-36046-y

Table 1.

α-Glucosidase inhibitory activity of compounds 7a-p.

graphic file with name 41598_2023_36046_Figa_HTML.gif
Entry Compound X Y IC50 (μM)
1 7a H H 0.02 ± 0.00
2 7b H 4-F 43.10 ± 0.20
3 7c H 2-Cl 61.70 ± 0.30
4 7d H 4-Me 0.04 ± 0.00
5 7e 4-NO2 H 3.60 ± 0.50
6 7f. 4-NO2 4-F 8.90 ± 0.10
7 7g 4-NO2 2-Cl 0.06 ± 0.00
8 7h 4-NO2 4-Me 0.01 ± 0.00
9 7i 4-Cl H 261.40 ± 1.80
10 7j 4-Cl 4-F 648.90 ± 1.90
11 7k 4-Cl 2-Cl 492.47 ± 2.80
12 7l 4-Cl 4-Me 289.20 ± 0.30
13 7m 4-OMe H 0.86 ± 0.01
14 7n 4-OMe 4-F 23.70 ± 0.10
15 7o 4-OMe 2-Cl 23.30 ± 0.70
16 7p 4-OMe 4-Me 101.80 ± 0.40
Acarbose 752.10 ± 1.10