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. 2023 Apr 20;14(3):1468–1481. doi: 10.1002/jcsm.13234

Table 2.

Correlation of PDFF % MRI and muscle biopsy changes

Muscles Correlation coefficients
Biopsy fat fraction % P‐value Biopsy pathology grade P‐value
Semimembranosus PDFF % 0.85 <0.001 0.78 <0.001
Vastus lateralis PDFF % 0.68 0.005 0.77 <0.001
Rectus femoris PDFF % 0.17 0.530 0.18 0.516

Note: Spearman correlation coefficients are shown for the correlation between MRI measured PDFF of the respective muscles on the one hand and the fat fraction and Rochester University Histopathology Grade on muscle biopsy on the other hand. Significant P‐values are marked in bold.

Abbreviations: MRI, magnetic resonance imaging; PDFF, proton density fat fraction.