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. 2023 May 1;14(3):1546–1557. doi: 10.1002/jcsm.13242

Table 2.

Histology results from the tibialis anterior, including donor age, muscle fibre size and shape metrics from laminin segmentations, and fibrosis proportions derived from Sirius‐red stains

BMD (n = 24) Controls (n = 8) P‐value
Age, years [range] 41 [19–66] 40 [23–48] 0.76
Laminin fibre segmentation
Cross‐sectional area, μm2 6009 [2207] 3903.9 [1428.8] 0.008*
Minimum Feret diameter, μm 72.5 (7.9) 63.2 (6.9) 0.006*
Perimeter, μm 321.3 [61.8] 258.3 [49.7] 0.010*
Circularity 0.75 [0.03] 0.76 (0.02) 0.222
Sirius‐red fibrosis analysis
Fibrosis proportion, % 21.7 [5.6] 14.9 [3.4] <0.001*

Note: Data are expressed as mean (standard deviation) or median [interquartile range].

Abbreviation: BMD, Becker muscular dystrophy.

*

Statistically significant at the P = 0.05 level.