Skip to main content
. 2021 Apr 30;7(2):111–126. doi: 10.52601/bpr.2021.200040

Table 1. Examples of GWAS application in bacterial pathogens.

Diseases Species Sample size phenotype Sig. viriants Reference
DR: Drug resistance;
IPD: Invasive pneumococcal disease.
Tuberculosis M. tuberculosis 161 DR ponA1 Farhat et al. 2013
1526 DR 13 loci Farhat et al. 2019
161 DR 10 SNPs Zhang et al. 2013
1000 DR rpoA, B, C; eis Casali et al. 2014
123 DR 58 SNPs Chen and Shapiro 2015
3651 DR 23 SNPs Walker et al. 2015
284 DR ald Desjardins et al. 2016
6465 DR 43 SNPs Coll et al. 2018
710 DR 2 SNPs Hicks et al. 2019
177 DR 25 SNPs Kavvas et al. 2020
Pneumonia S. pneumoniae 3701 DR 51 SNPs Chewapreecha et al. 2014
1680 DR 4,317 SNPs Mobegi et al. 2017
K. pneumoniae 328 Virulence & DR wzi Holt et al. 2015
Pyomyositis S. aureus 90 Virulence 121 SNPs Laabei et al. 2014
75 DR 1 SNPs Alam et al. 2014
518 Morbidity PVL encoding genes Young et al. 2019
Gastroenteritis C. jejuni 192 Host adaptation 7 genes Sheppard et al. 2013
102 Biofilm formation 46 genes Pascoe et al. 2015
600 Survival 20 genes Yahara et al. 2017
166 Diagnostic Markers 25 genes Buchanan et al. 2017
Meningitis Pneumococcus 4572 DR & IPD pbp1bA641C Li et al. 2019a