Table 2. Examples of mGWAS reveal association between host genetic variants and microbial traits.

Cohort size	Host type	Phenotypes	Sig. variants	Sequencing	Reference
474	Human	Taxa	NOD2 & 48 SNPs	16S	Knights et al. 2014
93	Human	Taxa	83 SNPs	16s	Blekhman et al. 2015
184	Human	Taxa	8 SNPs	16S	Davenport et al. 2015
1126 twin pairs	Human	β-diversity & taxa	31 loci	16S	Goodrich et al. 2016
1514	Human	Taxa & pathways	74 loci	WGS	Bonder et al. 2016
1561	Human	taxa	58 loci	16S	Turpin et al. 2016
1812	Human	β-diversity & taxa	82 loci	16S	Wang et al. 2016
725 twin pairs	Human	MTs	2 loci	16S	Demmitt et al. 2017
298	Human	Taxa	–	16S & WGS	Kolde et al. 2018
1882	Human	Taxa	–	16S & WGS	Rothschild et al. 2018
3880	Human	MTs	2 SNPs	16S	Hughes et al. 2020
18473	Human	Taxa	LCT gene	16S & WGS	Kurilshikov et al. 2020
1464	Human	Taxa & pathways	12 mbQTL	WGS	Hu et al. 2021
110	Mouse	Taxa	7 loci	16S	Org et al. 2015
196	A. thaliana	Taxa	–	16S	Horton et al. 2014