Table 1. Outline of clinical trials investigating the use of MSC in different neurological conditions.
| NCT number | Title | Status | Study results |
Conditions | Characteristics | Completion date |
| NCT03632135 |
Standard chemotherapy vs. chemotherapy guided by cancer stem cell test in recurrent glioblastoma |
Recruiting | N/A | Recurrent glioblastoma | Phase III | January 2022 |
| NCT02824653 |
Allogenic bone marrow mesenchymal stem cells infusion in patients with steroid-refractory GVHD |
Completed | N/A | GVHD | Phase I Phase II |
December 2018 |
| NCT02795052 |
Neurologic stem cell treatment study |
Recruiting | N/A |
Neurologic disorders, nervous system diseases, neurodegenerative diseases, neurological disorders, stroke, traumatic brain injury; cadasil, chronic traumatic; encephalopathy, cerebral infarction, cerebral ischemia, and 10 more |
N/A | June 2021 |
| NCT01982682 |
Allogeneic hematopoietic stem cell transplantation for high-risk hematologic malignancies using one haploidentical donor |
Completed | Results available |
Hematopoietic/lymphoid cancer |
Phase II | March 2017 |
| NCT00798811 |
High-dose chemotherapy with autologous stem cell rescue in paediatric high-risk brain tumours |
Active | N/A | Brain tumour | Phase II | December 2021 |
| NCT00179803 |
Stem cell transplant for high-risk central nervous system (CNS) tumours |
Unknown | N/A |
Glioblastoma, astrocytoma, pineoblastoma, rhabdoid tumor, and supratentorial neoplasms |
Phase II Phase III |
September 2009 |
| NCT00002619 |
Chemotherapy followed by bone marrow or peripheral stem cell transplantation in treating patients with glioblastoma multiforme or brain stem tumours |
Completed | Has results |
Brain and central nervous system tumours |
Phase II | April 2000 |
| NCT01922908 |
Mesenchymal stromal cells for ischemic stroke |
Withdrawn | N/A | Ischemic stroke | − | April 2018 |
| NCT03384433 |
Allogenic mesenchymal stem cell derived exosome in patients with acute ischemic stroke |
Completed | N/A | Ischemic stroke | Phase I | December 2019 |
| NCT00875654 |
Intravenous stem cells after ischemic stroke |
Completed | N/A | Ischemia stroke | Phase II | October 2017 |
| NCT03291366 |
Mesenchymal stem cells in central nervous system injury 2017 |
Active, not recruiting | N/A | Central nervous system injury | Phase I Phase II |
January 2022 |
| NCT04063215 |
A clinical trial to determine the safety and efficacy of hope biosciences autologous mesenchymal stem cell therapy for the treatment of traumatic brain injury and hypoxic-ischemic encephalopathy |
Recruiting | N/A | Traumatic brain injury | Phase I Phase II |
August 2021 |