Table 2. Treatment Characteristics of the ITT Patient Groups.
| Characteristic | Patientsa | P valueb | |
|---|---|---|---|
| Replanning arm (n = 66) | Standard arm (n = 65) | ||
| Type of chemotherapy | |||
| Fluorouracil and carboplatin | 9 (13.6) | 9 (13.8) | .43 |
| Cisplatin | 42 (63.6) | 47 (72.3) | |
| Cetuximab | 15 (22.7) | 9 (13.8) | |
| IMRT modality, by tomotherapy vs arc therapy | 17 (25.8) | 16 (24.6) | >.99 |
| CT scans including initial planning, No. | |||
| 1 | 2 (3.0) | 58 (89.2) | <.001 |
| 2 | 2 (3.0) | 7 (10.8) | |
| 6 | 51 (77.3) | 0 | |
| 7 | 11 (16.7) | 0 | |
| ≥35 Cycles of radiotherapy | 63 (95.5) | 65 (100) | .24 |
| Interruption of treatment | |||
| No | 33 (50.0) | 32 (49.2) | .30 |
| Definitive | 3 (4.5) | 0 | |
| Temporary | 30 (45.5) | 33 (50.8) | |
| Overall duration of radiotherapy, mean (SD), d | 50.4 (8.6) | 51.6 (4.3) | .81 |
| Reason for interruptionsc | |||
| Not related to toxic effects | 22 (33.3) | 27 (41.5) | .36 |
| Toxic effects | 11 (16.7) | 6 (9.2) | |
| No interruption | 33 (50.0) | 32 (49.2) | |
Abbreviations: CT, computed tomography; IMRT, intensity-modulated radiotherapy; ITT, intent to treat.
a
Data are presented as the number (percentage) of patients unless otherwise indicated.
b
Fisher exact test or Wilcoxon rank sum test.
c
Interruption was defined as at least 1 day.