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. 2023 Mar 15;9(3):710. doi: 10.18063/ijb.710

Table 2. Bioink in corneal regeneration.

Materials 3D printing method Cells type Clinical status Follow-up result Ref.
Gelatin-methacryloyl (GelMA) SLA Human corneal stromal cells In vitro [97]
Corneal stroma-derived decellularized extracellular matrix Extrusion printing Human turbinate derived mesenchymal stem cells (HTMSCs) In vivo rabbit 4 weeks, lattice pattern generation with printed collagen fibrils [98]
Bioink containing human recombinant laminin-521 & Human collagen I Laser-assisted bioprinting Human embryonic stem cell derived limbal epithelial stem cells (HESC-LESC), human adipose tissue derived stem cells (HASCs) In vitro [64]
Poly (ε-caprolactone)-poly (ethylene glycol) & GelMa Direct writing Limbal stromal stem cells (LSSCs) In vivo rat 3 months, stromal tissue regeneration [99]
Type I collagen-based bioinks Drop-on-demand (dod) bioprinting Corneal stromal keratocytes (CSK) In vitro [100]
Gelatin-methacryloyl (GelMA) Extrusion printing Human corneal keratocytes (HKs) In vitro [101]
Chitosan and polyvinylalcohol Extrusion printing Human adipose tissue-derived mesenchymal stem cells (HASCs) In vitro [102]
Sodium alginate and methacrylated type I collagen Extrusion printing Corneal keratocytes In vitro [65]
Polyvinyl acetate/collagen Electrospun Human keratocytes (HKs) and human corneal epithelial cells (HCECs) In vitro [103]
Gelatin & Sodium alginate Extrusion printing human corneal epithelial cells (HCECs) In vitro [63]
Cornea-derived decellularized extracellular matrix (dECM) Extrusion printing Human turbinate derived mesenchymal stem cells (hTMSCs) In vitro [104]