TABLE 2.
Estimates between diet variables and global cognition
| Predictor variable | Adjusted for age, sex, education, BMI, and statins |
Additional adjustment for TEI |
||
|---|---|---|---|---|
| β (95% CI) | P value | β (95% CI) | P value | |
| CFr | −0.027 (−0.043, −0.012) | <0.001 | −0.022 (−0.039, −0.005) | 0.011 |
| eCarb | −0.030 (−0.045, −0.016) | <0.0001 | −0.026 (−0.040, −0.011) | <0.001 |
| eFat | 0.024 (0.006, 0.042) | 0.010 | 0.017 (−0.003, 0.038) | 0.090 |
| eProt | 0.007 (−0.021, 0.034) | 0.64 | 0.013 (−0.017, 0.043) | 0.41 |
Abbreviations: CFr, log-ratio carbohydrates/fat; eCarb, digestible carbohydrates by E%; eFat, total fat by E%; eProt, protein by E%; TEI, total energy intake.
Mixed effects linear regression using data on diet and cognition from year 0, 1, and 2, adjusted for time, time × randomization group, plus indicated covariates, with study site and subject as random factors. Statins refers to use of any cholesterol-lowering drug. Diet and cognition measured on a z-scale (n = 1247).