Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Feb 20;9(4):337–342. doi: 10.1093/ehjcvp/pvad009

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

PMC Copyright notice

Plasma LDL-cholesterol levels according to the genetic inhibition of PCSK9 (as a function of PCSK9-R46L variant) in the UK Biobank. The plot depicts data from 382 813 individuals from the UK Biobank [219 301 women (pink symbols), 163 512 men (blue symbols)] free for lipid-lowering therapies. The y-axis showed LDL-C plasma levels (mmol/L) of individuals and the x-axis show groups of individuals based on their sex and genetic status. PCSK9, proprotein convertase subtilisin/kexin type 9; REF (0/0), non-carriers of the PCSK9-R46L variant; HET (0/1), heterozygous carriers of the PCSK9-R46L variant; HOM (1/1), homozygous carriers of the PCSK9-R46L variant; LDL-C, low-density lipoprotein cholesterol; SD, standard deviation to the mean.