FIGURE 2.

Molecular characterization of six neuroendocrine carcinoma of the gastrointestinal system (GIS‐NEC) cell lines and four small cell lung carcinoma (SCLC) cell lines. A, Mutations/abnormal splicing/gene expression of TP53 and RB1 genes, immunoblotting showing protein expression of p53 and Rb, and gene expression of master transcription factors in six GIS‐NEC and four SCLC cell lines. GAPDH was used as a loading control. B, Principal component analysis of six GIS‐NEC and four SCLC cell lines using 2500 highly variant genes