TABLE 1.
Correlation between circular RNA nuclear receptor‐interacting protein 1 (circNRIP1) expression and clinicopathological features in papillary thyroid cancer tissues (n = 102)
| Characteristic | n | circNRIP1 | p value | |
|---|---|---|---|---|
| High expression(%) | Low expression(%) | |||
| Gender | ||||
| Male | 39 | 18(46.2) | 21(53.8) | 0.541 |
| Female | 63 | 33(52.4) | 30(47.6) | |
| Age, years | ||||
| <55 | 60 | 33(55.0) | 27(45.0) | 0.227 |
| ≥55 | 42 | 18(42.9) | 24(57.1) | |
| Tumor size, cm | ||||
| <2 | 55 | 22(40.0) | 33(60.0) | 0.029* |
| ≥2 | 47 | 29(61.7) | 18(38.3) | |
| Extrathyroidal extension | ||||
| Yes | 35 | 20(57.1) | 15(42.9) | 0.297 |
| No | 67 | 31(46.3) | 36(53.7) | |
| LNM | ||||
| Yes | 64 | 36(56.2) | 28(43.8) | 0.101 |
| No | 38 | 15(39.5) | 23(60.5) | |
| Multifocality | ||||
| Yes | 32 | 17(53.1) | 15(46.9) | 0.669 |
| No | 70 | 34(48.6) | 36(51.4) | |
| TNM staging | ||||
| I‐II | 86 | 38(44.2) | 48(55.8) | 0.006* |
| III–IV | 16 | 13(81.2) | 3(18.8) | |
| Hashimoto thyroiditis | ||||
| Yes | 27 | 13(48.1) | 14(51.9) | 0.822 |
| No | 75 | 38(50.7) | 37(49.3) | |
Abbreviation: LNM, lymph node metastasis.
*
Statistically significant (p < 0.05).