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. 2023 Mar 6;114(6):2306–2317. doi: 10.1111/cas.15760

FIGURE 6.

FIGURE 6

Schematic model of the polarization mechanism of tumor‐associated macrophages (TAMs). SLC3A2, as a metabolic switch on lung adenocarcinoma (LUAD) cells, induces macrophage phenotype reprogramming to M2 type through arachidonic acid (AA), and promotes the progress of lung adenocarcinoma. TME, tumor microenvironment