Table 4.
Predictors of HAVB/CHB and 30-d PPM/ICD requirement after TAVI in patients with pre-existing RBBB
| Univariable analyses |
Multivariable analyses |
|||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p value | OR | 95% CI | p value | |
| Procedural HAVB/CHB (n = 261) | ||||||
| STS risk score, per 1% increase | 1.09 | 1.02-1.16 | 0.008 | 1.08 | 1.01-1.15 | 0.030 |
| Aortic valve area, per 0.1-cm2 decrease | 1.27 | 1.07-1.52 | 0.008 | 1.23 | 1.03-1.48 | 0.024 |
| Implantation depth relative to the NCC, per 1-mm increase | 1.27 | 1.09-1.48 | 0.002 | 1.25 | 1.07-1.46 | 0.004 |
| Delayed HAVB/CHB (n = 205)∗ | ||||||
| General anesthesia (vs. conscious sedation) | 3.25 | 1.11-9.53 | 0.032 | 1.03 | 0.29-3.68 | 0.96 |
| Predilation | 6.47 | 2.30-18.21 | <0.001 | 4.02 | 1.22-13.23 | 0.022 |
| Implantation depth relative to the NCC, per 1-mm increase | 1.53 | 1.18-1.99 | 0.001 | 1.34 | 1.01-1.79 | 0.044 |
| 30-d PPM/ICD requirement (n = 261) | ||||||
| LVOT calcification | 2.37 | 1.24-4.53 | 0.009 | 1.77 | 0.89-3.52 | 0.11 |
| Self-expanding valve (vs. balloon-expandable valve) | 3.31 | 1.07-10.28 | 0.038 | 1.72 | 0.48-6.19 | 0.41 |
| Predilation | 3.18 | 1.69-5.98 | <0.001 | 1.94 | 0.96-3.90 | 0.064 |
| Implantation depth relative to the NCC, per 1-mm increase | 1.42 | 1.21-1.66 | <0.001 | 1.32 | 1.11-1.55 | 0.001 |
Notes. Predictors were examined in multivariable logistic regression models including variables with a p value at <0.05 in univariable models (Supplemental Table 3). In multivariable models, missing data for aortic valve area, implantation depth, and LVOT calcification were handled with multiple imputation.
CHB = complete heart block, CI = confidence interval, HAVB = high-degree atrioventricular block, ICD = implantable cardioverter defibrillator, LVOT = left ventricular outflow tract, NCC = noncoronary cusp, OR = odds ratio, PPM = permanent pacemaker, RBBB = right bundle branch block, TAVI = transcatheter aortic valve implantation.
Includes patients who did not develop procedural HAVB/CHB.