Table 2.
Result of all variable analysis of included studies in meta-analysis
| Variables | Studies (n) | Participant (n) | Mean difference | Effect size | Publication bias | ||||
|---|---|---|---|---|---|---|---|---|---|
| MD (95% CI) | Q test | I2(%) | Effect size (95% CI) | Q test | I2(%) | Egger’s t value (95% CI) | |||
| 2-h pain score | 3 | 227 | 0.966 (0.057, 1.876) * | 21.408 | 90.658 *** | 0.791 (0.480, 1.103) *** | 2.503 | 20.104 | 0.238 (− 53.858, 51.879) |
| 4-h pain score | 5 | 360 | 1.153 (0.480, 1.826) *** | 93.987 | 95.744 *** | 1.522 (0.552, 2.491) ** | 63.631 | 93.714 *** | 1.324 (− 10.004, 24.254) |
| 8-h pain score | 6 | 511 | 0.839 (0.381, 1.297) *** | 49.079 | 89.812 *** | 1.084 (0.364, 1.803) ** | 70.278 | 92.885 *** | 2.126 (− 3.005, 22.656) |
| 12-h pain score | 4 | 328 | 0.999 (0.282, 1.716) ** | 12.994 | 76.912 ** | 0.720 (0.249, 1.190) ** | 12.497 | 75.994 ** | 0.875 (− 40,558, 26.853) |
| 24-h pain score | 8 | 619 | 0.884 (0.274, 1.494) ** | 87.891 | 92.036 *** | 0.892 (0.441, 1.344) *** | 42.381 | 85.843 *** | 2.347 (− 0.362, 17.285) |
| 48-h pain score | 7 | 534 | 0.892 (0.441, 1.344) *** | 42.381 | 85.843 *** | 1.005 (0.432, 1.578) *** | 56.123 | 89.309 *** | 2.474 (− 0.292, 15.262) |
| 72-h pain score | 3 | 231 | 0.556 (0.131, 0.981) * | 3.738 | 46.501 | 0.511 (0.181, 0.840) ** | 2.930 | 31.737 | 1.185 (− 44.972, 37.301) |
| 4-h VAS | 4 | 316 | 1.956 (0.232, 3.680) * | 43.757 | 93.144 *** | 0.792 (0.229, 1.356) ** | 0.520 | 82.149 *** | 3.190 (− 33.256, 4,939) |
| 8-h VAS | 5 | 467 | 2.822 (0.555, 5.090) * | 46.274 | 91.356 *** | 0.648 (0.110, 1.186) * | 31.805 | 87.423 *** | 0.340 (− 35.898, 44.461) |
| 12-h VAS | 3 | 268 | 2.934 (0.738, 5.130) ** | 25.189 | 92.060 *** | 0.929 (0.581, 1.277) *** | 3.637 | 45.007 | 0.291 (− 99.140, 94.701) |
| 24-h VAS | 6 | 515 | 1.965 (0.634, 3.297) ** | 31.177 | 83.963 *** | 0.561 (0.165, 0.956) ** | 23.922 | 79.099 *** | 0.555 (− 15.519, 20.280) |
| 48-h VAS | 5 | 430 | 0.996 (0.136, 1.856) * | 17.271 | 76.840 ** | 0.553 (0.344, 0.763) *** | 4.633 | 13.664 | 1.540 (− 12.257, 4.262) |
| 72-h VAS | 3 | 231 | 0.556 (0.132, 0.981) * | 3.735 | 46.457 | 0.511 (0.181, 0.840) ** | 2.930 | 31.751 | 1.185 (− 44.977, 37.305) |
| Total rescue analgesia | 5 | 361 | 11.237 (3.574, 18.899) ** | 1.860 | 0 | 0.275 (0.068, 0.483) ** | 2.908 | 0 | 1.007 (− 4.340, 8.354) |
| Hospital stay time | 3 | 268 | 0.071 (− 0.031, 0.174) | 1.043 | 0 | 0.131 (− 0.109, 0.371) | 1.734 | 0 | 0.927 (− 14.890, 12.866) |
P < 0.05, *; P < 0.01, **; P < 0.001, ***